The aim of our research team is to reduce the burden of osteoporotic fractures. We use medical imaging technologies to explore bone and muscle responses to activity or neurologic impairment, and evaluate new methods for image analysis. We conduct epidemiologic studies to inform fracture risk assessment algorithms. We conduct clinical trials to investigate the effects of exercise interventions for reducing fracture risk in high risk individuals. We lead knowledge dissemination and translation activities, and implementation studies to move research on exercise for older adults into practice.